Oral and gastrointestinal colonization of Lactobacillus is established during early childhood, and it plays an important role in human health.
One of the beneficial Lactobacillus species, Lactobaccilus plantarum 299v (Lp299v), has been shown to have exceptional abilities including: a) mucosal binding and colonization; b) tolerance to a variety of stresses; c) prevention of inflammatory changes in disease models; d) regulation of bacterial overgrowth; and e) enhancement of vaccine efficacy.
Effect of Lp299v Clinical Research:
Multiple randomized, controlled, and double-blind studies with Lp299v supplementation have shown significant improvements in gastrointestinal symptoms including IBS. For example, Neidzelin K et al. have reported complete disappearance of abdominal pain in a treatment group after the 4 weeks of Lp299v (20 billion cfu/day) supplementation. Resolution of irregularity, and other IBS associated symptoms such as flatulence, abdominal pain, constipation, diarrhea, and bloating in one study were also documented, and the difference was significant when compared to the placebo group.
Safety: Lp299v has been widely commercialized and consumed by many nations for decades without any reported complications. The natural occurrence of this beneficial bacteria in food and human mucosa, and the human origin of the commercial probiotic Lp299v may explain its well-accepted tolerance in people.
Jarrow Formulas Ideal Bowel Support 299v Each vegetarian capsule contains a minimum of 10 billion L. plantarum 299v viable cells to help alleviate digestive issues and bloating. Does not require refrigeration.
Enzymatic Therapy Pearls Elite boasts a special delivery system that ensures active cultures survive in stomach acid and arrive in intestines intact.
Dr. Ohhira’s Probiotics 12 Plus This non-dairy organic supplement contains a proprietary blend of live lactic acid bacteria that helps fight pathenogenic bacteria.
Udo’s Choice Children’s Probiotic contains 8 child-specific bacterial strains at an appropriate strength. Each capsule is contains at least 2 billion viable cells.